An Fgf8-Dependent Bistable Cell Migratory Event Establishes CNS Asymmetry
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چکیده
منابع مشابه
An Fgf8-Dependent Bistable Cell Migratory Event Establishes CNS Asymmetry
Neuroanatomical and functional asymmetries are universal features of the vertebrate CNS, but how asymmetry is generated is unknown. Here we show that zebrafish fgf8 mutants do not elaborate forebrain asymmetries, demonstrated by the failure of the parapineal nucleus to migrate from its initial midline position to the left side of the brain. Local provision of Fgf8 restores the asymmetric migrat...
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ژورنال
عنوان ژورنال: Neuron
سال: 2009
ISSN: 0896-6273
DOI: 10.1016/j.neuron.2008.11.030